Jeff Dunham: Spark of Insanity is the second Comedy Central special featuring Jeff Dunham. It features Dunham in Washington, D.C.
- Walter: A grumpy old Vietnam War veteran who has a negative and sarcastic view on today's world.
- Achmed the Dead Terrorist: A former suicide bomber who doesn't seem like a threat.
- Melvin the Superhero Guy: A superhero who is based off of superheroes, and is a stereotype for them.
- Peanut: A Woozle-like creature who is wacky in many ways.
- José Jalapeño on a Stick: A pepper on a stick who is typically paired with Peanut.